South Africa: Cape Town, Treating Drug-resistant TB & HIV
Site Mentor: James Brust, MD (james.brust@einsteinmed.edu, 718-920-6482)
Columbia University Faculty Liason: Michael T. Yin, MD, MS
Research opportunities available at this site/project/program:
Summer Research Projects, Scholarly Projects, and Research Year
Thematic Research Areas at this site/project/program:
Infectious Diseases
Global Pop funds students from the following CUIMC Schools at this site:
VP&S and MSPH
Language requirement:
No
Potential activities that could be carried out by students at this site/project:
Literature Review, IRB development, Interview tool development, Attend regular Team/site Meetings, Data collection, Data monitoring, Data analysis, Program monitoring and evaluation, Summarizing/Disseminating results, and Shadowing
About Projects with Dr. Brust
Project Title: Optimizing treatment for drug-resistant tuberculosis and HIV in South Africa
Project Information: With funding from NIH, we are examining the emergence of resistance to bedaquiline or clofazimine in patients who interrupt therapy for MDR or XDR tuberculosis. We are enrolling participants in South Africa from 5 different provinces, measuring plasma drug concentrations and sequencing sputum M. tuberculosis isolates to study correlations between drug pharmacokinetics and the emergence of resistance-conferring mutations.
Student Participation: Remote, Hybrid, and In-person opportunities
Travel Location(s): Cape Town, South Africa
Number of students: 1-2
Mentored Research Project in 2023
Outcome and Diagnosis of HIV-associated Pneumocystis Pneumonia
Student: Anne Berhe (VP&S)